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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Hepatology. 2012 Dec;56(6):2316–2327. doi: 10.1002/hep.25938

Fig. 4. Enhanced liver inflammation in SOD1mu mice is suppressed by NOX1/4 inhibition.

Fig. 4

Livers from WT or SOD1mu mice were analyzed after 12 injections of CCl4 or vehicle (n=5). In last half period of injections, some mice in each strain were treated by NOX1/4 inhibitor daily. Immunohistochemistry for (A) F4/80 and (B) its quantification are shown (original magnification ×100). (C, D) Hepatic mRNA expression of CD68 and TNF-α was measured by quantitative real-time PCR. (E) Serum ALT levels were measured. NI: NOX1/4 inhibitor. *P<0.05