Table 1.

Characteristics of Study Sample, by NSAID use at Baseline

	Total Study Sample (n=160,143)		Women not currently using NSAIDs at baseline (n=103,100)		Women currently using NSAIDs at baseline (n=57,043)
	N	%	N	%	N	%
Enrollment Status
Any Clinical Trial	67,822	42.35	44,106	42.78	23,716	41.58
Observational Study	92,321	57.65	58,994	57.22	33,327	58.42
Age at Baseline (years)
50–54	21,398	13.36	15,399	15.81	5,999	10.52
55–59	31,741	19.82	21,999	21.34	9,742	17.08
60–69	71,902	44.90	45,268	43.91	26.634	46.69
70–79	35,102	21.92	20,434	19.82	14,668	25.71
Body Mass Index at Baseline (kg/m2)
<25.0	55,788	35.14	38,340	37.53	17,448	30.84
25.0–29.9	55,144	34.74	35,447	34.70	19,697	34.81
≥30.0	47,805	30.12	28,367	27.77	19,438	34.35
Smoking History
No	80,616	50.75	52,703	51.55	27,913	49.30
Yes	78,234	49.25	49,529	48.45	28,705	50.70
Duration (years)a<9	18,154	23.20	11,881	23.99	6,273	21.85
10–19	16,366	20.92	10,560	21.32	5,806	20.23
20–29	16,468	21.05	10,448	21.09	6,020	20.97
30–39	14,036	17.94	8,622	17.41	5,414	18.86
40+	10,330	13.20	6,169	12.56	4,161	14.50
History of Diabetes
No	150,560	94.08	97,607	94.73	52,953	92.90
Yes	9,475	5.92	5,428	5.27	4,047	7.10
History of Cardiovascular Disease
No	124,099	82.18	83,044	85.58	41,055	76.07
Yes	26,905	17.82	13,991	14.42	12,914	23.93
History of Ulcerative Colitis
No	156,289	98.90	100,442	98.85	55,847	98.98
Yes	1,742	1.10	1,166	1.15	576	1.02
Colonoscopy Received in Prior Five Years b
No	29,059	37.18	18,054	37.34	11,005	36.93
Yes	49,097	62.82	30,302	62.66	18,795	63.07
Family History of Colorectal Cancer
No	121,962	83.46	78,809	83.65	43,153	83.13
Yes	24,163	16.54	15,405	16.35	8,758	16.87

^aNumbers and percentages for duration calculated among women reporting positive smoking history

^bNumbers and percentages calculated among women reporting ever receiving a colonoscopy