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. 2012 Sep 18;107(9):1525–1533. doi: 10.1038/bjc.2012.421

Table 3. Correlation (r) between uracil catabolism and 5FU catabolism by 5FU treatment regimen.

  Treatment regimen
  Mayo daily schedule Weekly schedule
  n =38 n =27
  UH2 UH2/U UH2 UH2/U
5FU T1/2 −0.164 −0.098 −0.206 −0.381*
5FU Cl 0.201 −0.045 0.023 0.101
5FUH2 AUC 0.493** 0.449** 0.481** 0.153

Abbreviations: 5FU=5-fluorouracil; AUC=area under the curve; FUH2=dihydrofluorouracil; U=uracil; UH2=dihydrouracil.

*P<0.05, **P<0.01.