Skip to main content
. 2012 Aug 28;4(5):938–948. doi: 10.3892/etm.2012.687

Table I.

Characteristics of the studies included in this meta-analysis.

Author (Refs.) Site Group Source Sample Genotype
Genotyping method P-value (HWE) for controls Adjustment
c1/c1 c1/c2 c2/c2
Lin et al (16) Linxian County, Henan Province T ESCC and EAC 45 36 6 3 PCR-RFLP 0.345 Age, gender
C PB 45 20 22 3
Tan et al (17) Linxian County, Henan Province T ESCC 150 107 31 12 PCR-RFLP 0.009 Age, gender, smoking
C PB 150 66 77 7
Shi (20) Linzhou City, Henan Province T EC 116 74 37 5 PCR-RFLP 0.922 Age, gender, smoking, fermented vegetable
C HB 106 46 48 12
Xi’an City, Shaanxi Province T EC 71 39 28 4 PCR-RFLP 0.368
C HB 62 30 24 8
Gao et al (21) Huai’an City, Jiangsu Province T EC 144 83 44 13 PCR-RFLP 0.525 Age, gender, tea, smoking, alcohol
C PB 233 140 75 14
Shi et al (23) Wuhan City, Hubei Province T EC 98 72 19 7 PCR-RFLP 0.039 Age, gender
C HB 120 54 45 21
Gao et al (22) Huai’an City, Jiangsu Province T EC 93 55 31 7 PCR-RFLP 0.20 Age, gender, smoking, drinking, dietary habits
C PB 196 121 62 13
Shi et al (24) Nanjing City, Jiangsu Province T EC 78 48 24 6 PCR-RFLP 0.141 Age, gender, smoking, alcohol
C HB 118 60 42 16
Yin et al (25) Huai’an City, Jiangsu Province T EC 106 52 49 5 PCR-RFLP 0.411 Age, gender
C HB 106 55 45 6
Lu et al (19) Kazakh, Xinjiang Autonomous Region T ESCC 104 81 20 3 PCR-RFLP <0.001 Age, gender
C PB 104 25 74 5
Li (26) Taiyuan City, Shanxi Province T EC 60 32 18 10 PCR-RFLP 0.781 Age, gender, smoking, drinking habits
C PB 199 101 69 29
Liu et al (28) Huai’an City, Jiangsu Province T ESCC 77 34 33 10 PCR-RFLP 0.91 Age, gender
C PB 79 45 29 5
Dong et al (27) Gansu Province T EC 120 84 26 10 PCR-RFLP 0.428 Age, gender
C HB 120 57 44 19
Xia et al (31) Jingjiang City, Jiangsu Province T ESCC 45 30 12 3 PCR-RFLP 0.708 Not reported
C HB 45 26 17 2
Qin et al (30) Kazakh, Xinjiang Autonomous Region T EC 120 94 23 3 PCR-RFLP 0.29 Age, gender, dietary habits
C PB and HB 240 128 90 22
Guo et al (29) Lanzhou City, Gansu Province T ESCC 80 57 16 7 PCR-RFLP <0.001 Age, gender
C PB 480 225 180 75
Yang (32) Feicheng City, Shandong Province T ESCC 27 19 8 0 PCR-RFLP 0.442 Age, gender, alcohol, education, smoking
C PB 44 31 11 2
Zhang and Wu (33) Gansu Province T EC 129 75 40 14 PCR-RFLP 0.443 Age, gender
C PB 156 70 56 21

Characteristics of studies included in this meta-analysis. T, case subjects; C, control subjects; PB, population-based; HB, hospital-based; ESCC, esophageal squamous cell carcinoma; EAC, esophageal adenocarcinoma; EC, esophageal cancer; HWE, Hardy-Weinburg equilibrium; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism.