Table 2.
Controls† | FA exposed Workers† | P value†† | |||||
---|---|---|---|---|---|---|---|
n | Mean | (std) | n | mean | (std) | ||
|
|||||||
CD3+CD4+ | |||||||
CD4 naïve (CD45RA+CCR7+) | 41 | 301 | 131 | 32 | 261 | 140 | 0.14‡‡ |
CD4 memory (CD45RA−) | |||||||
Central Memory (CD45RA-CCR7+) | 41 | 198 | 80 | 32 | 208 | 74 | 0.88¥¥ |
Effector Memory (CD45RA-CCR7−) | 41 | 229 | 82 | 32 | 212 | 105 | 0.09 |
T Regulation subset | |||||||
CD4+CD25+ | 51 | 82 | 38 | 43 | 72 | 33 | 0.16 |
CD4+FoxP3+ | 51 | 50 | 22 | 43 | 41 | 18 | 0.04 |
CD25+FoxP3+ | 51 | 53 | 23 | 43 | 42 | 19 | 0.008 |
CD3+CD8+ | |||||||
CD8 naïve (CD45RA+CCR7+) | 41 | 227 | 122 | 32 | 185 | 102 | 0.15¥ |
CD8 memory (CD45RA−) | |||||||
Central Memory (CD45RA-CCR7+) | 41 | 12 | 9 | 32 | 13 | 8 | 0.74¥¥ |
Effector Memory (CD45RA-CCR7−) | 41 | 169 | 76 | 32 | 135 | 64 | 0.018 |
unadjusted mean (±SD) cells/μl blood;
P value compares exposed workers to controls, adjusted for age and sex;
adjusted for age, sex, and smoking;
adjusted for age, sex, and BMI;
adjusted for age, sex, smoking, infection, BMI, and alcohol use.