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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Am J Ind Med. 2012 Jul 5;56(2):252–257. doi: 10.1002/ajim.22088

Table 2.

Lymphocyte subset cell counts [mean ± standard deviation (std)] among formaldehyde (FA) exposed workers and unexposed controls.

Controls FA exposed Workers P value††
n Mean (std) n mean (std)

CD3+CD4+
CD4 naïve (CD45RA+CCR7+) 41 301 131 32 261 140 0.14‡‡
CD4 memory (CD45RA−)
  Central Memory (CD45RA-CCR7+) 41 198 80 32 208 74 0.88¥¥
  Effector Memory (CD45RA-CCR7−) 41 229 82 32 212 105 0.09
T Regulation subset
  CD4+CD25+ 51 82 38 43 72 33 0.16
  CD4+FoxP3+ 51 50 22 43 41 18 0.04
  CD25+FoxP3+ 51 53 23 43 42 19 0.008
CD3+CD8+
CD8 naïve (CD45RA+CCR7+) 41 227 122 32 185 102 0.15¥
CD8 memory (CD45RA−)
  Central Memory (CD45RA-CCR7+) 41 12 9 32 13 8 0.74¥¥
  Effector Memory (CD45RA-CCR7−) 41 169 76 32 135 64 0.018

unadjusted mean (±SD) cells/μl blood;

††

P value compares exposed workers to controls, adjusted for age and sex;

¥

adjusted for age, sex, and smoking;

‡‡

adjusted for age, sex, and BMI;

¥¥

adjusted for age, sex, smoking, infection, BMI, and alcohol use.