Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Sep 19;287(46):38992–39000. doi: 10.1074/jbc.M112.348037

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 5. — Compound D737 rescues cells from the cytotoxic effect of Aβ42. The results represent percentage of viable cells compared with untreated cells. a, effect of D737 on the cytotoxicity of Aβ42 oligomers. 20 μm Aβ42 was incubated in the absence (black bars) or presence (gray bars) of 40 μm D737 for the indicated times under oligomerization conditions before being added to PC12 cells. b, D737 showed slight dose-dependent rescue from toxicity caused by Aβ42 oligomers formed during 1 h of incubation. c, D737 showed significant dose-dependent rescue from cytotoxicity caused by Aβ42 oligomers formed after 24 h of incubation. d, effect of D737 on the cytotoxicity of Aβ42 fibrils. 20 μm Aβ42 was incubated under fibrillization conditions in the absence (black bars) or presence (gray bars) of 40 μm D737 for the indicated times before being added to PC12 cells.