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. 2012 Sep 10;287(46):39224–39232. doi: 10.1074/jbc.M112.393843

TABLE 1.

Enriched peptides against MBP-NS3-4A protease and inhibitory effect of the peptides on NS3–4A activity

Comparison of IC50 values and Ki values of derived peptides. Constant sequence parts are colored in blue, and homologies are colored in orange. Substituted residues in later stages of optimization are colored in red. Peptide K5-66-R is a scrambled control peptide. Measurements were carried out in duplicate, the curves were fitted using GraphPad Prism with a nonlinear regression model, and the standard deviation is shown.

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