Table 2. Beta-catenin expression in 24 adult soft-tissue lesions as evaluated by tissue microarray-based immunohistochemistry.
Case | Age (years) | Site | Histopathological diagnosis | Membranous/cytoplasmic β-catenin (%) | Nuclear β-catenin (%) |
---|---|---|---|---|---|
1 | 59 | Subcutis | Angiosarcoma | 50% C | 0 |
2 | 64 | Subcutis | Angiosarcoma | >25% M | 0 |
3 | 59 | Subcutis | Angiosarcoma | >25% C | 0 |
4 | 74 | Subcutis | Angiosarcoma | 100% M/C | 0 |
5 | 64 | Subcutis (thigh) | Liposarcoma | <25% C | <5% |
6 | 72 | Kidney | Myxoid liposarcoma | 60% C | 25% |
7 | 56 | Subcutis (buttock) | Liposarcoma | 15% C | 0 |
8 | 76 | Subcutis (abdomen) | Myxoid liposarcoma | 100% M | 0 |
9 | 76 | Subcutis | Liposarcoma | 50% M/C | 0 |
10 | 54 | Retroperitonaeum | Liposarcoma | 50% C | 5% |
11 | 74 | Subcutis | Clear cell sarcoma | 100% C | 0 |
12 | 70 | Subcutis (arm) | Pleomorphic sarcoma | 80% C | 10% |
13 | 69 | Nose | Sarcoma | 10% M | 0 |
14 | 57 | Retroperitoneum | Fibrosarcoma | 100% M/C | 0 |
15 | 75 | Paravesical region | High-grade fibrosarcoma | 100% C | 0 |
16 | 70 | Subcutis (arm) | Sarcoma | 100% M/C | 5% |
17 | 47 | Kidney | Sarcoma | 50% C | 0 |
18 | 80 | Subcutis | Synovial sarcoma | 95% M/C | 0 |
19 | 35 | Iliac region | Leiomyosarcoma | 100% C | <10% |
20 | 90 | Subcutis | Leiomyosarcoma | 100% M/C | 0 |
21 | 43 | Retroperitonaeum | Leiomyosarcoma | 40% C | 0 |
22 | 90 | Subcutis | Leiomyosarcoma | 100% M/C | 0 |
23 | 83 | Subcutis (back) | Leiomyosarcoma | 100% M/C | 0 |
24 | 84 | Abdomen | Rhabdomyosarcoma | 100% M/C | 0 |
C, cytoplasmic; M, membranous; M/C, mixed membranous and cytoplasmic. Mean spot percentage of positive cells. Staining intensity was graded from + (faint) to +++ (strong).