Figure 1.

Immunohistochemical staining of the expression of SP-C in lung tissues. A, B, C, D) From preterm infants with respiratory distress syndrome who were ventilated at elevated oxygen concentrations for 1–3 days, 4–8 days, 9–16 days and >16 days, respectively. E) From premature infants who died without lung disorders; the positive staining of SP-C was restricted to the type II alveolar epithelial cells; SP-C positive cells are more numerous in preterm infants with respiratory distress syndrome after 4 days duration of mechanical ventilation at elevated oxygen concentrations than in premature infants who died without lung disorders.