Table 3.
Brain Volumes for Regions of Interest in Participants
| Brain Region | Mean Volume | SD | Z Scoresa |
| Grey matter cm3 | 680.61 | 59.14 | −0.09 |
| White matter cm3 | 474.95 | 47.48 | −0.13 |
| Cerebrospinal fluid (CSF) cm3 | 361.04 | 43.15 | 0.28 |
| Right hippocampus mm3 | 2845.28 | 336.22 | −0.12 |
| Left hippocampus mm3 | 2786.8 | 359.99 | −0.81* |
| Total hippocampus mm3 | 5632.09 | 635.01 | −0.48 |
| Right amygdala mm3 | 2320.02 | 341.54 | 0.27 |
| Left amygdala mm3 | 2196.08 | 357.73 | −0.13 |
| Total amygdala mm3 | 4516.10 | 652.34 | 0.09 |
| Hippocampus/amygdala total mm3 | 10148.19 | 1167.86 | −0.06 |
a
Z Scores derived to contextualize participants results using data from controls (n = 21) from Northern Ireland First-Episode Psychosis Study, selected to individually match study participants for both sex and age. Controls were scanned concurrently and neuroanatomical data were generated contemporaneously, using identical methods to those described herein.
*Significant reduction, P < .05.