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. Author manuscript; available in PMC: 2013 Oct 31.
Published in final edited form as: J Am Chem Soc. 2012 Oct 19;134(43):17900–17903. doi: 10.1021/ja3090498

Figure 2.

Figure 2

Genetic verification of the caz biosynthetic cluster in C. globosum. A) Organization of the 65 kb caz cluster. B) (i) LC-MS analysis (observed at 360 nm) of azaphilones produced by wild-type C. globosum; (ii) formation of 8 in the ΔcazE mutant; and abolishment of the production of 3–7 in the (iii) ΔcazF and (iv) ΔcazM mutants.