Table III.

Association between polymorphisms and patient clinical features.

A, 5′-UTR
Variable	2R/2R+2R/3R n (%)	3R/3R+3R/4R n (%)	P-value
Age (years)
≤70	28 (35.4)	51 (64.6)
>70	7 (63.6)	4 (36.4)	0.072
Gender
Male	21 (46.7)	24 (53.3)
Female	14 (31.1)	31 (68.9)	0.130
Smoking status
Non-smoker	22 (39.3)	34 (60.7)
Smoker	13 (38.2)	21 (61.8)	0.921
Line of treatment
First-line	12 (35.3)	22 (64.7)
Second-line or further	23 (41.1)	33 (58.9)	0.586
Cycle
≤4	27 (42.2)	37 (57.8)
>4	8 (30.8)	18 (69.2)	0.314
B, 3′-UTR
Variable	Ins6/del6+del6/del6 n (%)	Ins6/ins6 n (%)	P-value
Age (years)
≤70	74 (93.7)	5 (6.3)
>70	9 (81.8)	2 (18.2)	0.064
Gender
Male	42 (93.3)	3 (6.7)
Female	41 (91.1)	4 (8.9)	0.987
Smoking status
Non-smoker	51 (91.1)	5 (8.9)
Smoker	32 (94.1)	2 (5.9)	0.601
Line of treatment
1st-line	32 (94.1)	2 (5.9)	0.601
2nd-line or further	51 (91.1)	5 (8.9)
Cycle
≤4	59 (92.2)	5 (7.8)
>4	24 (92.3)	2 (7.7)	0.985