Table III.
Factors increasing the risk for hepatocellular carcinoma (HCC), determined by multivariate analysis.
| Parameters | Hazard ratio | 95% CI | P-value |
|---|---|---|---|
| AST (IU/l) | |||
| ≥71 | 1.27 | 0.72–2.26 | 0.411 |
| ALT (IU/l) | |||
| ≥60 | 1.40 | 0.81–2.43 | 0.229 |
| AFP (ng/ml) | |||
| <6 | 1 | - | - |
| 6–19 | 2.22 | 1.13–4.38 | 0.006 |
| ≥20 | 2.09 | 1.03–4.23 | 0.003 |
| Interferon therapy (%) | |||
| No therapy | 1 | - | - |
| Non-SVR | 0.99 | 0.55–1.80 | 0.989 |
| SVR | 0.46 | 0.14–1.57 | 0.218 |
CI, confidence interval; AST, aspartate transaminase; ALT, alanine transaminase; AFP, α-fetoprotein; SVR, sustained virological response.