Table III. Classification of unspliced intragenic nEPTs.
Each nEPT location was classified by visual inspection of mapped EPT on the genome alongside the published gene models, six reading frame translations, and RNA-Seq read alignments using IGV. EPTs were grouped into common categories based on the most likely type of addition or correction suggested.
Category | Count |
---|---|
Other splice fix | 115 |
Missing gene end | 99 |
Splice fix at 3′ exon | 86 |
Insertion/deletion | 56 |
Different strand/frame | 53 |
Alternative splicing | 18 |
Retained intron | 15 |
Gene fusion correction | 11 |
Alternate start codon | 11 |
Noncanonical start codon | 7 |
Other/unexplained | 33 |
Total: | 504 |