Table I. Number and percentage of identified phagosomal proteins matching Gene Ontology (GO) terms and KEGG pathways.
| GO term: | Phagosome | Whole cell | Enrichment |
|---|---|---|---|
| GO:0015986: ATP synthesis coupled proton transport | 14 (1.25%) | 16 (0.21%) | 5.82 |
| GO:0009617: response to bacterium | 40 (3.56%) | 53 (0.71%) | 5.02 |
| GO:0009144: purine nucleoside triphosphate metabolic process | 29 (2.58%) | 47 (0.63%) | 4.11 |
| GO:0030036: actin cytoskeleton organization | 42 (3.74%) | 107 (1.43%) | 2.61 |
| GO:0006886: intracellular protein transport | 41 (3.65%) | 109 (1.46%) | 2.5 |
| GO:0016192: vesicle-mediated transport | 56 (4.98%) | 157 (2.10%) | 2.37 |
| KEGG pathways: | Phagosome | Whole cell | Enrichment | p value |
|---|---|---|---|---|
| Ribosome | 42 (3.26%) | 86 (0.65%) | 5.05 | <105 |
| Protein processing in endoplasmic reticulum | 22 (1.71%) | 66 (0.50%) | 3.44 | <105 |
| Protein export | 11 (0.85%) | 17 (0.13%) | 6.69 | <105 |
| Phagosome | 18 (1.40%) | 40 (0.30%) | 4.65 | <105 |
| Oxidative phosphorylation | 30 (2.33%) | 66 (0.50%) | 4.70 | <105 |
| Metabolic pathways | 114 (8.85%) | 499 (3.75%) | 2.36 | <105 |
| Endocytosis | 19 (1.48%) | 39 (0.29%) | 5.03 | <105 |
| Citrate cycle (TCA cycle) | 15 (1.16%) | 30 (0.23%) | 5.17 | <105 |
| Biosynthesis of secondary metabolites | 40 (3.11%) | 174 (1.31%) | 2.38 | <105 |
| Alanine, aspartate and glutamate metabolism | 11 (0.85%) | 20 (0.15%) | 5.68 | 1 × 105 |
| Proteasome | 14 (1.09%) | 38 (0.29%) | 3.81 | 3 × 105 |
| Glycolysis/Gluconeogenesis | 12 (0.93%) | 28 (0.21%) | 4.43 | 3 × 105 |