Table II. Enriched functional categories and canonical pathways in mESC and mEpiSC intersecting proteins with PluriNet or PluriNetWork.
Union Set (mESC and mEpiSC) overlap with PluriNet |
Union Set (mESC and mEpiSC) overlap with PluriNetWork |
||
---|---|---|---|
Functional categories | p value | Functional categories | p value |
Connective Tissue Development and Function | 1.96E-05 | Organismal development | 9.48E-20 |
Organismal Survival | 2.20E-05 | Embryonic Development | 3.41E-09 |
Embryonic Development | 5.53E-05 | Tissue development | 1.85E-08 |
Nervous System Development and Function | 5.53E-05 | Organ development | 3.96E-08 |
Tissue Development | 5.53E-05 | Hematological System Development and Function | 1.68E-07 |
Canonical pathways | p value | Canonical pathways | p value |
---|---|---|---|
Mismatch Repair in Eukaryotes | 2.52E-15 | DNA Methylation and Transcriptional Repression Signaling | 3.8E-21 |
Cell Cycle Control of Chromosomal Replication | 2.89E-15 | Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency | 2.26E-09 |
Hereditary Breast Cancer Signaling | 8.75E-11 | Chronic Myeloid Leukemia Signaling | 4.18E-07 |
Role of CHK Proteins in Cell Cycle Checkpoint Control | 4.01E-09 | Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency | 1.15E-06 |
Role of BRCA1 in DNA Damage Response | 8.21E-09 | Huntington's Disease Signaling | 1.67E-06 |