Quantitative AI map of TG2 with its related proteins. Normalized transamidating activities and dissociation constants (Kd) of TG2 with 16 proteins were used to construct an integrative proteomic map. In this map, the node volume represents the transamidating activity and the distance between the node and TG2 indicates the Kd value. ALDOA, aldolase A; ANXA, annexin A1; Bcl2, B-cell lymphoma 2; E-cad, E-cadherin; FI, fibrinogen; FN, fibronectin; GCA, grancalcin; GST, gluatathione S-transferase; HSA, human serum albumin; OPN, osteopontin; RB1, retinoblastoma; S100A7, S100 calcium binding protein A7; SMAD2, Sma- and Mad-related protein 2; SNCA, α-synuclein.