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. 2012 Jul 25;11(11):1105–1122. doi: 10.1074/mcp.M111.016592

Table III. Biological networks in which 115 differently expressed proteins identified in the nuclear proteome are involved.

No GO processes Total nodes Root nodes Pathway p-Value z-Score g-Score
1 Response to DNA damage stimulus (46.0%), DNA metabolic process (46.0%), DNA repair (38.0%) 50 25 5 1.53e-52 70.06 76.31
2 DNA metabolic process (48.0%), DNA replication (30.0%), cell cycle (46.0%) 51 18 1 1.53e-34 49.84 51.09
3 Regulation of actin polymerization or depolymerization (11.6%), organelle organization (34.9%), cellular component movement (23.3%) 50 17 0 6.77e-33 49.04 49.04
4 DNA metabolic process (43.8%), cell cycle (45.8%), cell cycle phase (33.3%) 50 16 2 5.37e-30 44.71 47.21
5 Response to stress (52.1%), response to organic substance (41.7%), response to stimulus (68.8%) 50 15 0 1.08e-27 41.89 41.89