Fig. 4.
Fatty-acid oxidation as the preferred fuel source in transgenic muscle. A: Immunoblot of plantaris lysate for PSer293-PDH and PDH. Quantitation is shown in B. C: Expression of PDK4 in plantaris. D: Fatty acid oxidation rate of C2C12 myoblasts overexpressing adeno-GFP or adeno-Nur77, corrected for non-fatty acid mediated oxygen consumption. Error bar represents SD. E: Acylcarnitine and organic acid concentrations from gastrocnemius lysate. Open bar: wild-type; Closed bar: transgenic (n = 7–9, male). WT, wild-type; TG, transgenic. *P < 0.05; **P < 0.01; ***P < 0.001.