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. Author manuscript; available in PMC: 2012 Nov 9.
Published in final edited form as: Chem Rev. 2010 Dec 2;111(1):68–85. doi: 10.1021/cr1000817

Figure 4.

Figure 4

Primary structure of the AHL synthases and the pC-HSL synthase RpaI. A sequence and topology diagram shows the sequences of several AHL synthases mapped to the structural descriptions of the AHL synthases LasI and EsaI. The grey shaded regions are the most conserved sequence blocks within the AHL synthase family. The eight conserved residues of the AHL synthase family are highlighted in solid colors, and those that are similar among AHL synthases are boxed. Below the sequences are shown the alpha helices (magenta) and beta strands (cyan) observed in the structures of EsaI and LasI. The lettering ‘a’ and ‘p’ indicate the amino acid residues proposed to interact with the acyl chain or phosphopantetheine moieties of acyl-ACP, respectively.