Table 3. Multivariate analysis of various predictive factors for the presence of non-sentinel node metastases.
Factors | Odds ratio (95% CI) | P -value |
---|---|---|
Pathological tumour size | ||
⩽2 cm vs >2 cm | 2.600 (1.137–5.946) | 0.024 |
Nuclear grade | ||
1+2 vs 3 | 1.051 (0.337–3.279) | 0.932 |
Oestrogen receptor status | ||
Absent vs present | 0.996 (0.267–3.716) | 0.995 |
HER2 status | ||
Negative + unknown vs positive | 1.855 (0.647–5.321) | 0.25 |
Lymphovascular invasion | ||
Absent vs present | 3.472 (1.230–9.799) | 0.019 |
CK19 mRNA in SLN (copies μl−1) | ||
<5.0 × 103 vs ⩾5.0 × 103 | 3.757 (1.569–8.997) | 0.003 |
Abbreviations: CI=confidence interval; CK19=cytokeratin 19; SLN=sentinel lymph node.