TABLE 3.
Subgroup | Observed events | Expected events* | HR; 95% CI | P-value | Absolute risk/ 100,000 PYAR | Excess risk/ 100,000 PYAR | Attributable percentage |
---|---|---|---|---|---|---|---|
Sex | |||||||
Females | 233 | 81 | 2.89; 2.47–3.39 | <0.001 | 115 | 75 | 65 |
Males | 173 | 62 | 2.79; 2.32–3.36 | <0.001 | 143 | 92 | 64 |
Age | |||||||
10–19 yrs | 39 | 10 | 3.80; 2.53–5.71 | <0.001 | 27 | 20 | 74 |
20–39 yrs | 69 | 21 | 3.33; 2.47–4.48 | <0.001 | 116 | 81 | 70 |
40–59 yrs | 146 | 58 | 2.53; 2.08–3.07 | <0.001 | 198 | 119 | 60 |
≥60 | 152 | 53 | 2.85; 2.33–3.48 | <0.001 | 355 | 230 | 65 |
Calendar period | |||||||
-1989 | 82 | 27 | 3.00; 2.27–3.97 | <0.001 | 96 | 64 | 67 |
1990–1999 | 181 | 66 | 2.74; 2.29–3.28 | <0.001 | 113 | 72 | 64 |
2000–2008 | 143 | 48 | 2.96; 2.42–3.61 | <0.001 | 184 | 122 | 66 |
HR, Hazard ratio; CI, Confidence interval; PYAR, Person-years at risk.
Reference is general population comparator cohort.
Expected number of events in patients with celiac disease was derived from the observed number of events divided by the HR.