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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 18;264(3):351–360. doi: 10.1016/j.taap.2012.09.007

Figure 4.

Figure 4

EPA- and DHA-mediated vasodilation is significantly attenuated in abdominal aorta of CYP1A1 KO mice. (A) EPA-mediated relaxation (% U46619 preconstriction), (B) DHA-mediated relaxation (% U46619 preconstriction), in abdominal aorta from CYP1A1 WT and KO mice. Data represent mean ± SEM and were analyzed by two-way, repeated measures ANOVA, using post hoc Holm-Sidak comparisons; *p < 0.05, compared to wildtype ((n=6/genotype).