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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Sep 18;264(3):351–360. doi: 10.1016/j.taap.2012.09.007

Figure 7.

Figure 7

Responses to potassium channel inhibitors do not differ between CYP1A1 WT and KO mice. (A) DHA-mediated vasodilation after pre-incubation with the BK channel blocker, iberiotoxin (IBTX) in CYP1A1 WT and (B) KO mice. (C) DHA-mediated relaxation after pre-incubation with both IBTX and the voltage gated potassium channel blocker, 4-AP in CYP1A1 WT and (D) KO mice. Data represent mean ± SEM and were analyzed by two-way, repeated measures ANOVA, using post hoc Holm-Sidak comparisons; *p < 0.05, compared to wildtype (n=4–6/genotype).