Table 1.
Comparison of immunohistochemical scores across patient groups sorted by histological subtype or clinical / molecular characteristics
| Compared groups | Statistical test used | Result | |
|---|---|---|---|
|
EZH2 | |||
| PDSS and MPSS and BPSS |
Kruskal-Wallis |
P < 0.001 |
|
| PDSS vs. MPSS |
Mann–Whitney |
P < 0.001 |
|
| PDSS vs. BPSS |
Mann–Whitney |
P = 0.001 |
|
| MPSS vs. BPSS |
Mann–Whitney |
NS |
|
|
H3K27me3 | |||
| PDSS and MPSS and BPSS |
Kruskal-Wallis |
P < 0.001 |
|
| PDSS vs. MPSS |
Mann–Whitney |
P < 0,001 |
|
| PDSS vs. BPSS |
|
P = 0.001 |
|
| MPSS vs. BPSS |
Mann–Whitney |
NS |
|
|
Ki-67 | |||
| PDSS and MPSS and BPSS |
1 |
P < 0.001 |
|
| PDSS vs. MPSS |
Mann–Whitney |
P < 0,001 |
|
| PDSS vs. BPSS |
Mann–Whitney |
NS |
|
|
Compared groups |
EZH2 |
Ki-67 |
H3K27me3 |
|
Gender | |||
| Male vs. female |
NS |
NS |
NS |
|
Age | |||
| ≤25 y/o vs. >25 y/o |
NS |
NS |
NS |
|
Location | |||
| Central vs. peripheral |
NS |
NS |
NS |
|
Tumor size | |||
| <5cm vs. ≥5cm |
P < 0.001 |
NS |
P = 0.032 |
|
Distant metastasis | |||
| Present vs. absent |
P < 0.001 |
P = 0.021 |
P = 0.003 |
|
Fusion gene | |||
| SYT-SSX1 vs. SYT-SSX2 | NS | NS | NS |
(PDSS: poorly differentiated synovial sarcoma; MPSS: monophasic synovial sarcoma; BPSS: biphasic synovial sarcoma; NS: not significant).