Table 2.
Association of high EZH2, H3K27me3, and Ki-67 scores with the risk of large tumor size and distant metastasis (NS: non-significant)
| Relative Risk | 95% Confidence Interval | P value | |
|---|---|---|---|
|
High EZH2 score | |||
|
All Cases |
|
|
|
| -Tumor size >5 cm |
4.09 |
1.78-9.40 |
P<0.001 |
| -Distant metastasis |
2.20 |
1.49-3.23 |
P<0.001 |
|
Cases other than PDSS |
|
|
|
| -Tumor size >5 cm |
4.00 |
1.63-9.82 |
P=0.02 |
| -Distant metastasis |
2.09 |
1.36-3.21 |
P=0.02 |
|
High H3K27me3 score | |||
|
All Cases |
|
|
|
| -Tumor size >5 cm |
2.25 |
1.07-4.73 |
NS |
| -Distant metastasis |
1.64 |
1.09-2.46 |
NS |
|
Cases other than PDSS |
|
|
|
| -Tumor size >5 cm |
1.12 |
0.20-6.17 |
NS |
| -Distant metastasis |
1.20 |
0.55-2.60 |
NS |
|
High Ki-67 score | |||
|
All Cases |
|
|
|
| -Tumor size >5 cm |
2.62 |
1.29-5.34 |
P=0.04 |
| -Distant metastasis |
1.71 |
1.17-2.51 |
NS |
|
Cases other than PDSS |
|
|
|
| -Tumor size >5 cm |
1.75 |
0.39-7.88 |
NS |
| -Distant metastasis | 0.98 | 0.24-4.03 | NS |