Table 4.
Univariate analysis of local control at one and two years per target (n = 153)
| Local control per target at 1 year (%) | Local control per target at 2 years (%) | p* | |
|---|---|---|---|
|
Total dose |
|
|
|
|
= 45 Gy |
92.3 (82.1 – 96.8) |
79.1 (61.6 – 89.3) |
|
|
< 45 Gy |
72.0 (56.4 – 82.8) |
66.5 (50.3 – 78.5) |
0.019 |
|
Target diameter |
|
|
|
|
> 50 mm |
74.6 (54.6 – 86.8) |
63.0 (39.8 – 79.3) |
|
|
< 50 mm |
87.5 (77.9 – 93.1) |
78.8 (65.9 – 87.3) |
0.019 |
|
GTV volumes |
|
|
|
|
> 100 cc |
81.8 (58.5 – 92.8) |
62.3 (31.0 – 82.6) |
|
|
< 100 cc |
84.4 (74.9 – 90.5) |
76.8 (64.9 – 85.0) |
0.063 |
|
PTV volumes |
|
|
|
|
> 200 cc |
72.6 (50.3 – 86.2) |
59.9 (35.3 – 77.7) |
|
| < 200 cc | 87.2 (78.0 – 92.8) | 79.0 (66.7 – 87.2) | 0.014 |
* Log-rank test (CI at 95%).