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. 2012 Nov 1;8(11):1701–1705. doi: 10.4161/auto.21332

Table 1. Components of the receptor protein complexes involved in autophagy.

Process Cargo Ligand Receptor Scaffold Atg8 family protein Refs.
Cvt pathway (yeasts)
prApe1 complex
prApe1 propeptide
Atg19
Atg11
Atg8
23, 24, 26, 27
Ams1 complex
Ams1
Atg19, Atg34
Atg11
Atg8
38, 39
Glycophagy (mammals)
Glycogen particles
Glycogen
STBD1
-
GABARAP
58, 59
Aggrephagy (worms)
PGL granules
PGL-3
SEPA-1
EPG-2
LGG-1
60, 61
Aggrephagy (mammals)
Mutant SOD1 aggregates
Mutant SOD1
SQSTM1
-
LC3
20, 21
STAT5A_ΔE18 aggregates
STAT5A_ΔE18
SQSTM1
-
-
22
Ubiquitinated protein aggregates
Ub
SQSTM1, NBR1
WDFY3
LC3
4352
Midbophagy (mammals)
Midbodies
Ub
SQSTM1
-
LC3
62
CEP55
NBR1
-
-
63
Pexophagy (yeasts)
Peroxisomes
Pex3, Pex14
Atg30
Atg11, Atg17
-
17, 18
Pexophagy (mammals)
Peroxisomes
Pex14
-
-
LC3
64
Ub
SQSTM1
-
LC3
65
Mitophagy (yeasts)
Mitochondria
Outer membrane
Atg32
Atg11
Atg8
28, 29
Mitophagy (mammals)
Mitochondria
Outer membrane
BNIP3, BNIP3L, FUNDC1
-
LC3, GABARAP
3033
Ub
SQSTM1
-
LC3
6672
Xenophagy (mammals) Viruses
Viral capsid proteins
SQSTM1
-
LC3
73
Ubiquitinated bacteria
Ub
SQSTM1, CALCOCO2, OPTN
-
LC3
3436, 7476
Bactericidal factors
FAU, Ub
SQSTM1
-
LC3
77
Membrane remnants, damaged vesicles Ub, LGALS8 SQSTM1, CALCOCO2 - LC3 78, 79