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. 2012 Oct 1;1(7):1004–1016. doi: 10.4161/onci.21057

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Figure 6. Antitumor effects of peptide mimics and paclitaxel in a transplantable mouse model. Wild type BALB/c mice (n = 5) at the age of 5–7 weeks were challenged with TUBO cells. Mice were then treated intravenously with paclitaxel, HER-2 peptides, VEGF peptides or a combination of paclitaxel and the peptides. Results (A and B) indicate a delay in tumor growth and development in the treated groups and the effect was more evident with the combination of paclitaxel and the peptides (*p < 0.001). Mice that were treated with both peptides and paclitaxel showed a significant reduction in tumor weight a (p < 0.001) as compared with control animals, while mice treated with either peptides alone or paclitaxel alone showed a significant difference with p < 0.005. Tumor measurement was performed using calipers and error bars represent standard deviations from the mean.