Table 1. Amino acid sequences and molecular weight of HER-2 and VEGF peptide mimics.
Designation | Peptide | Sequence | M.Wt. (da) |
---|---|---|---|
MVF-HER-2-266-296(CYC) MVF-HER2 | 266-296 peptide with one disulfide bond. | MVF-LHCPA LVTYNTDTFESMPNPEGRYTFGASCV-COOH | 4927 |
VEGF-P3(CYC)P3 | 76-96 peptide with one disulfide bond | CH3CONH-76-ITMQ-79-C-92-GIHQGQHPKIRMI-80-C-EMSF-96 | 2527 |
RI-VEGF-P4(CYC)P4 | 96-76 peptide with D amino acids and one disulfide bond | CH3CONH-(D)-96-FSME-80-C-92-IMRIKPHQGQHIG-79-CQMTI-76 | 2527 |
Sequences of amino acids are represented from N to C-terminal except for the retro inverso peptide RI-VEGF-P4-CYC that was synthesized in the reverse order and using D-amino acids