Figure 6. Cytotoxicity studies of TUDCA in primary human RPTE cells.

Cells were treated with either vehicle (control) or 15 to 1200 µM of TUDCA for 24 hours. A, TUDCA was not cytotoxic in concentrations from 15 to 600 µM. Significant cytotoxicity was seen only with 1200 µM of TUDCA, as compared to the vehicle (p<0.05). B, TUDCA did not decrease cell viability in all the tested concentrations from 15 µM to 1200 µM. Results are expressed as mean ± standard deviation. All experiments were performed in triplicate. †p<0.05 from vehicle-treated control.