Figure 8. Survival pathway analysis following cryoinjury and treatment with TUDCA in primary human RPTE cells.

Phosphorylated ERK1/2 protein in cryoinjured cells that were treated with either vehicle (control) or 100 µM or 150 µM TUDCA as compared to uninjured cells (top panel). There was no difference in the amount of phosphorylated ERK1/2 between uninjured and cryoinjured cells treated with vehicle. Densitometry analysis of phosphorylated ERK1/2 (lower panel). Results are expressed as mean ± standard deviation. All experiments were performed in triplicate. §p<0.01 and †p<0.05 from vehicle-treated control. Cryo, cryoinjury.