A) Protein expression of total PPARγ in mesenteric arteries (n=5). B-D) Pressure-diameter relationship under active conditions (B), passive diameter curve determined in a Ca2+-free solution (C), % myogenic tone (D) is shown (NT, n=12; S-P467L, n=11). E) Vasoconstriction in response to 100 mmol/L KCl (n=9). F) Structural parameters in Ca2+-free condition (at 75 mmHg) (NT, n=11; S-P467L, n=12). * p<0.05 compared to NT. All data are mean±SEM