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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Invest Dermatol. 2012 Jul 26;133(1):78–86. doi: 10.1038/jid.2012.249

Figure 4. Increased apoptosis in Aurora-A deficient epidermis.

Figure 4

Top panel shows the immunodetection of active Caspase 3 in WT and Aurora-A−/− epidermis at E13.5. Bar= 25 μm. Bottom panel shows the quantitation of apoptosis found in developing skin of Aurora-Afl/fl; K14.Cre or WT embryos (n=2 embryos per genotype and timepoint). Columns represent average ± standard deviation. Note the absence of apoptotic cells in WT skin at any embryonic stage.