Skip to main content
. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Mol Cell Neurosci. 2012 Aug 27;51(3-4):89–100. doi: 10.1016/j.mcn.2012.08.010

Figure 3.

Figure 3

dnrx1 mediates some effects of dnlg1 overexpression. A. dnlg1-dependent overgrowth is blocked in dnrx1 mutants. Asterisk indicates that bouton number is significantly reduced when dnlg1 is overexpressed in dnrx1 mutants (BG487>ng1.1; dnrx1273/Df) compared to dnrx1 heterozygotes (BG487>ng1.1; dnrx1273/+). There is no significant difference between dnrx1 mutants overexpressing dnlg1 and those carrying only the gal4 driver. B. Inhibition of evoked release by dnlg1 depends on dnrx1. Overexpression of dnlg1 in muscles strongly reduces EJC size in dnrx1 heterozygotes, an effect that is significantly reduce in dnrx1 homozygotes, which do not differ from dnrx1 mutants carrying only the gal4 transgene. Asterisks indicate significant difference from BG487>ng1.1; dnrx1273/+. C. Muscle overexpression of dnlg1 reduces mEJC amplitude equally in dnrx1 mutants and heterozygotes (cyan and dark red lines, respectively), compared to dnrx1 mutant controls (dark blue line), indicating that dnrx1 function is not required for this phenotype.