Fig. 2.

UnitProt ID’s were provided for GORetriever to retrieve existing GO annotations for all proteins identified by MALDI-TOF/TOF. Subsequently, GO annotations were functionally categorized in CateGOrizer using a custom classification list (Supplemental Table 1). A pie chart is shown to display the percent of GO annotations that were listed for each GO category. A large number of putative binding partners of MnSOD were found to have functions relating to DNA repair/binding/replication and cell growth/death/apoptosis. These results indicate that MnSOD may act as a signaling mediator to activate the cellular adaptive response induced by LDIR.