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. 2012 Nov 12;199(4):589–598. doi: 10.1083/jcb.201203150

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© 2012 Li et al.

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Figure 4. — Constitutively SUMOylated ARL-13 fulfills the function of wild-type ARL-13. (A) ARL-13^K239,328R::SMO-1::GFP localizes normally. Arrow with solid line, ciliary base; arrow with broken line, middle-distal junction; arrowhead, ciliary tip. Bar, 5 µm. (B and C) ARL-13^K239,328R::SMO-1 fusion protein completely rescues the mislocalization of PKD-2 and ODR-10 in arl-13(gk513) cilia. Bar, 5 µm. (D and E) Expression of ARL-13^K239,328R::SMO-1 fully rescues the mating defects and chemotaxis defects of arl-13 animals. The data were analyzed using an unpaired Student’s t test and are presented as mean ± SEM (error bars); *, P < 0.01.