Figure 5.

PATJ and MBS interact genetically. (A) Reduction of MBS can partly rescue the embryonic lethality of PATJ^Δ1. Lethality data were averaged from three different experiments with 100 embryos each. (B) Embryos heterozygous for mbs^T541 and homozygous for PATJ^Δ1 show less cuticle defects than embryos homozygous for PATJ^Δ1. Cuticles were scored from three different experiments with total numbers of embryos of 174 (PATJ^Δ1/PATJ^Δ1) and 95 (PATJ^Δ1/mbs^T541, PATJ^Δ1). (C) Pupae homozygous for PATJ^Δ1 and heterozygous for mbs^T541 start metamorphosis in the imaginal discs. Note that pupae homozygous mutant for PATJ^Δ1 die soon after puparation, resulting in autolytic tissue, in which no imaginal discs can be identified. wt, wild type. Error bars indicate SDs. Bars, 100 µm.