Table 3. Predictors of pregnancy among HIV-positive women already accessing HIV clinical care at UK CHIC sites in 2000-2009.
Variables | Person- years |
Pregnancies | Pregnancy rate (per 100 person-years) |
95% CI | Relative Rate |
95% CI | p | Adjusted Relative Rate* |
95% CI | p | |
---|---|---|---|---|---|---|---|---|---|---|---|
Year of conception** | 38,097 | 1637 | 4.3 | 4.1 - 4.5 | 1.03 | 1.01-1.05 | <0.001 | 1.05 | 1.03-1.07 | <0.001 | |
Age group |
16-25 years | 3486 | 254 | 7.3 | 6.4 - 8.1 | 1.12 | 0.98-1.29 | 0.10 | 1.12 | 0.98-1.29 | 0.11 |
26-35 years | 15,927 | 1032 | 6.5 | 6.1 - 6.9 | 1.00 | - | - | 1.00 | - | - | |
36-49 years | 18,684 | 351 | 1.9 | 1.7 -2.1 | 0.30 | 0.26-0.34 | <0.001 | 0.29 | 0.25-0.33 | <0.001 | |
ART use CD4 count (cells/mm3) |
On ART | 22,512 | 890 | 4.0 | 3.7 - 4.2 | 0.82 | 0.74-0.91 | <0.001 | 0.95 | 0.85-1.05 | 0.32 |
≤200 | 6073 | 183 | 3.0 | 2.6 - 3.4 | 0.64 | 0.54-0.76 | <0.001 | 0.65 | 0.55-0.77 | <0.001 | |
201-350 | 8841 | 421 | 4.8 | 4.3 - 5.2 | 1.00 | - | - | 1.00 | - | - | |
>350 | 21,155 | 981 | 4.6 | 4.4 - 4.9 | 0.98 | 0.87-1.10 | 0.71 | 0.99 | 0.88-1.11 | 0.83 | |
NK | 2028 | 52 | 2.6 | 1.9 -3.3 | 0.54 | 0.41-0.72 | <0.001 | 0.52 | 0.39-0.68 | <0.001 | |
Ethnicity | White | 6993 | 203 | 2.9 | 2.5 - 3.3 | 0.62 | 0.52-0.73 | <0.001 | 0.67 | 0.57-0.80 | <0.001 |
Black-Caribbean | 1483 | 59 | 4.0 | 3.0 - 5.0 | 0.85 | 0.65-1.11 | 0.23 | 0.75 | 0.58-0.97 | 0.03 | |
Black-African | 24,837 | 1173 | 4.7 | 4.5 - 5.0 | 1.00 | - | - | 1.00 | - | - | |
Black-other | 1004 | 49 | 4.9 | 3.5 - 6.2 | 1.04 | 0.77-1.39 | 0.81 | 0.94 | 0.71-1.25 | 0.68 | |
Other | 2069 | 75 | 3.6 | 2.8 - 4.4 | 0.77 | 0.59-0.99 | 0.04 | 0.71 | 0.56-0.91 | 0.01 | |
Not reported | 1711 | 78 | 4.6 | 3.6 - 5.5 | 0.96 | 0.75-1.23 | 0.76 | 0.95 | 0.75-1.20 | 0.66 |
Where all variables in the table were included in the model.
As year is a continuous variable, RRs refer to an increase of one year.