Table 4.
Risk Reclassification.
| Model without CFR | Model with CFR | |||
|---|---|---|---|---|
| Diabetics | <1% Annual Risk | 1–3% Annual Risk | >3% Annual Risk | Total |
| Patients with Cardiac Death | ||||
| <1% Annual Risk | 1 (23.2) | 3.3 (76.8) | 0 (0) | 4.3 |
| 1–3% Annual Risk | 1 (5.4) | 8.7 (46.4) | 9 (48.1) | 18.7 |
| >3% Annual Risk | 0 (0) | 6.2 (8.8) | 64 (91.2) | 70.2 |
| Total | 2 | 18.2 | 73 | 93.2 |
| Patients without Cardiac Death | ||||
| <1% Annual Risk | 197 (75.9) | 62.7 (24.1) | 0 (0) | 259.7 |
| 1–3% Annual Risk | 177 (39.3) | 191.3 (42.5) | 82 (18.2) | 450.3 |
| >3% Annual Risk | 0 (0) | 86.8 (23.5) | 282 (76.5) | 368.8 |
| Total | 374 | 340.8 | 364 | 1078.8 |
| Non-Diabetics | <1% Annual Risk | 1–3% Annual Risk | >3% Annual Risk | Total |
| Patients with Cardiac Death | ||||
| <1% Annual Risk | 7.4 (32.2) | 15.5 (67.8) | 0 (0) | 22.9 |
| 1–3% Annual Risk | 2.4 (8.8) | 17.2 (62.7) | 7.8 (28.5) | 27.4 |
| >3% Annual Risk | 0 (0) | 2.3 (8.6) | 24.9 (91.4) | 27.3 |
| Total | 9.8 | 35.1 | 32.7 | 77.6 |
| Patients without Cardiac Death | ||||
| <1% Annual Risk | 890.6 (78.3) | 246.5 (21.7) | 0 (0) | 1137.1 |
| 1–3% Annual Risk | 106.6 (34.2) | 149.8 (48.1) | 55.2 (17.7) | 311.6 |
| >3% Annual Risk | 1.0 (1.2) | 14.7 (17.3) | 69.1 (81.5) | 84.7 |
| Total | 998.2 | 410.9 | 124.3 | 1533.4 |
Reclassification table for censored data using method of Steyerberg and Pencina29 from 2-year event data.
Parentheses indicate percentages of each pre-test category reclassified to each post-stress category.
CFR=coronary flow reserve.