Phosphorylated STAT3 (p STAT3) levels in injured hippocampus after fluid percussion injury (FPI). (A) Representative Western blots of protein homogenates from ipsilateral whole hippocampi (relative to FPI) of rats 6 h, 24 h, 48 h, and 1 week after FPI probed with pSTAT3 and STAT3 antibodies. (B) Quantification of pSTAT3 levels from FPI and sham-injured controls. (C) Representative Western blots of protein homogenates from contralateral whole hippocampi (relative to FPI) of rats 6 h, 24 h, 48 h, and 1 week after FPI probed with pSTAT3 and STAT3 antibodies. (D) Quantification of pSTAT3 levels from FPI and sham-injured controls. pSTAT3 levels were normalized to STAT3 levels and expressed as percent change compared to sham animals (*p<0.05, **p<0.001 for comparison of sham and FPI animals at the same time point; 6 h: n=5 for sham, 7 for FPI; 24 h: n=7 for sham, 6 for FPI; 48 h: n=6 for sham, 8 for FPI; 1 week: n=7 for sham, 7 for FPI; STAT3, signal transducer and activator of transcription 3).