Table 1.

Study participants

	Study Sample	Excluded	P value
Number	52	77
Age, years	63 ± 6	65 ± 8	0.12
Male gender, %	83	69	0.08
Race/ethnicity, %*
Non-Hispanic white	94	90	0.65
Non-Hispanic black	2	3
Hispanic	0	0
Non-Hispanic other	4	7
Ever-smoker, %	61	69	0.28
Height, cm	175 ± 10	169 ± 9	0.00
Weight, kg	86 ± 15	80 ± 15	0.03
Body mass index, kg/m2	28 ± 4	28 ± 5	0.72
Systemic hypertension, %	41	33	0.04
Corticosteroid use, %	38	33	0.07
PH therapy, %
Endothelin Receptor Antagonists	0	1	1.00
Phosphodiesterase-5 Inhibitors	0	4	0.16
FVC, % predicted	56 ± 15	66 ± 20	0.01
No.*	50	63
DLCO, % predicted	31 ± 10	36 ± 13	0.05
No.*	49	57
6MWD, m	407 ± 126	395 ± 142	0.57
No.*	47	36
NYHA Functional Class, %			0.04
I	4	22
II	56	36
III	38	36
IV	2	6
Hemodynamics
Right atrial pressure, mmHg	3.1 ± 2.7
Systolic PAP, mmHg	38.4 ± 12.6
Diastolic PAP mmHg	13.3 ± 6.6
Mean PAP, mmHg	22.3 ± 8.5
PCWP, mmHg	7.3 ± 3.2
PVR, dynes·s·cm−5	269.7 ± 195.8
Cardic index, L/min/m2	2.6 ± 0.6

Data shown as mean ± standard deviation or %.

^*Subset with available pulmonary function tests and 6MWD

Definition of abbreviations: FVC=forced vital capacity; DLCO=diffusion capacity of the lung for carbon monoxide; 6MWD=six-minute-walk distance; NYHA=New York Heart Association; PAP=pulmonary arterial pressures; PCWP=pulmonary capillary wedge pressure; PVR=pulmonary vascular resistance