Table 1.
|
Oocyte donors |
Infertile patients |
||||||
---|---|---|---|---|---|---|---|---|
|
Total |
Caucasian |
African |
Asian |
Total |
Caucasian |
African |
Asian |
(n = 62) | (n = 46) | (n = 10) | (n = 6) | (n = 536) | (n = 373) | (n = 81) | (n = 82) | |
Age(years) |
24.1 ± 3.71 |
24.2 ± 4.0 |
23.8 ± 2.2 |
23.7 ± 4.2 |
37.5 ± 5.21 |
37.8 ± 5.0 |
37.8 ± 5.3 |
36.1 ± 6.1 |
BMI(kg/m2) |
21.0 ± 2.82 |
20.6 ± 2.6 |
22.3 ± 2.8 |
21.5 ± 4.1 |
24.5 ± 5.12 |
24.5 ± 5.3 |
26.8 ± 5.1 |
22.2 ± 3.1 |
Estradiol(pg/mL) |
51.5 ± 26.1 |
52.5 ± 27.7 |
49.0 ± 19.4 |
46.2 ± 21.6 |
55.0 ± 37.8 |
57.0 ± 40.2 |
51.9 ± 34.5 |
48.8 ± 27.5 |
FSH(mIU/mL) |
6.8 ± 2.93 |
6.7 ± 3.0 |
6.6 ± 1.5 |
8.2 ± 2.8 |
12.3 ±10.13 |
12.5 ± 10.2 |
13.8 ± 13.4 |
10.2 ± 4.1 |
AMH(ng/mL) |
4.5 ± 2.94 |
4.3 ± 3.0 |
5.7 ± 1.9 |
4.6 ± 3.7 |
1.7 ± 2.24 |
1.6 ± 1.95 |
2.0 ± 2.9 |
2.3 ± 2.45 |
Oocyte yield |
17.7 ± 7.76 |
16.7 ± 6.67 |
23.7 ± 10.47,8 |
14.8 ± 6.48 |
8.1 ± 6.76 |
8.1 ± 6.8 |
7.9 ± 7.3 |
8.1 ± 5.9 |
FMR1 n (%) | ||||||||
norm |
33 (53.2) |
26 (56.5) |
4 (40.0) |
3 (50.9) |
315 (58.8) |
218 (58.4) |
41 (50.6) |
56 (68.3) |
het-norm/high |
6 (9.7) |
3 (6.5) |
1 (10.0) |
2 (33.3) |
86 (16.0) |
51 (13.7) |
18 (22.2) |
17 (20.7) |
het-norm/low |
19 (30.6) |
14 (30.4) |
5 (50.0) |
0 (0.0) |
107 (20.0) |
83 (22.3)9 |
19 (23.5)9 |
5 (6.1)9 |
hom |
4 (6.5) |
3 (6.5) |
0 (0.0) |
1(16.7) |
28 (5.2) |
21 (5.6) |
3 (3.7) |
4 (4.9) |
Primary infertility diagnosis n (%) | ||||||||
DOR |
N/A |
N/A |
N/A |
N/A |
279 (52.1) |
199 (47.5) |
38 (47.5) |
42 (51.2) |
Male factor |
N/A |
N/A |
N/A |
N/A |
134 (25.0) |
96 (25.7) |
18 (22.5) |
20 (24.4) |
Tubal Disease |
N/A |
N/A |
N/A |
N/A |
105 (19.6) |
70 (16.7) |
23 (25.3) |
12 (13.6) |
Endometriosis |
N/A |
N/A |
N/A |
N/A |
27 (5.0) |
21 (5.6) |
1 (1.3) |
5 (6.1) |
Uterine factors |
N/A |
N/A |
N/A |
N/A |
36 (6.7) |
20 (5.3) |
1 (1.2) |
15 (18.8) |
PCOS | N/A | N/A | N/A | N/A | 39 (7.3) | 27 (7.2) | 6 (7.5) | 6 (7.3) |
Values are presented as means ± SD. Subscripts denote significant differences at P ≤ 0.05 (chi-square, t-tests and Holm-Sidak post hoc comparisons). 1 P = 0.001; 2 P = 0.001; 3 P = 0.001; 4 P = 0.001; 5 P = 0.007; 6 P = 0.001; 7 P = 0.008; 8 P = 0.022; 9 P = 0.012.