Table 2.
Genes up regulated in the pediatric acute myeloid leukemia compared with normal control
| Gene | Description | NBM | AML | Fold change | P | |
|---|---|---|---|---|---|---|
| 1 |
BI RC5 |
Baculoviral IAP repeat containing 5,survivin |
34. 0496 |
221. 4575 |
6. 504 |
<0. 0001 |
| 2 |
FASLG |
Fas ligand (TNF superfamily, member 6) |
0. 0005 |
0. 0308 |
57. 068 |
<0. 0001 |
| 3 |
WT1 |
Wilms tumor 1 |
3. 7431 |
14. 5000 |
3. 874 |
<0. 0001 |
| 4 |
AREG |
Amphiregulin |
0. 9960 |
4. 6307 |
4. 649 |
<0. 0001 |
| 5 |
BCL2L1 |
BCL2-like 1 |
7. 6435 |
27. 1093 |
3. 547 |
0. 0002 |
| 6 |
HDAC4 |
Histone deacetylase 4 |
0. 0924 |
1. 0273 |
11. 117 |
0. 0002 |
| 7 |
CXCR4 |
Chemokine (C-X-C motif) receptor 4 |
24. 1547 |
1029. 2052 |
42. 609 |
0. 0004 |
| 8 |
HDAC7 |
Histone deacetylase 7 |
0. 7191 |
11. 6169 |
16. 155 |
0. 0006 |
| 9 |
S100A9 |
S100 calcium binding protein A9 |
0. 4583 |
185. 0090 |
403. 722 |
0. 0007 |
| 10 |
CD44 |
CD44 molecule (Indian blood group) |
2. 1648 |
312. 4866 |
144. 349 |
0. 0007 |
| 11 |
S100A8 |
S100 calcium binding protein A8 |
0. 0027 |
79. 0206 |
29736. 015 |
0. 0007 |
| 12 |
STMN2 |
Stathmin-like 2 |
0. 1887 |
1. 2260 |
6. 497 |
0. 0007 |
| 13 |
NF1 |
Neurofibromin 1 |
0. 0553 |
0. 3749 |
6. 775 |
0. 0009 |
| 14 |
CASP4 |
Caspase 4 |
0. 1491 |
218. 1356 |
1463. 137 |
0. 0009 |
| 15 |
BCL- 2 |
B-cell CLL/lymphoma 2 |
6. 1230 |
60. 3025 |
9. 849 |
0. 0009 |
| 16 |
BI K |
BCL2-interacting killer (apoptosis-inducing) |
3. 3040 |
26. 2063 |
7. 932 |
0. 001 |
| 17 |
PTEN |
Phosphatase and tensin homolog |
0. 5800 |
1. 4595 |
2. 516 |
0. 001 |
| 18 |
CASP1 |
Caspase 1 |
0. 3028 |
79. 9140 |
263. 884 |
0. 004 |
| 19 | CCL 5 | Chemokine (C-C motif) ligand 5 | 0. 0288 | 872. 0606 | 30237. 515 | 0. 004 |
NBM: Mean value of the gene expression in NBM group AML: Mean value of the gene expression in pediatric AML group.