Table 3.
Single parameters selected as significant predictors of coronary stenosis in separate myocardial segments
| Method | Parameter | Cut-off | AUC (95 % CI) | Sensitivity % (95 % CI) | Specificity % (95 % CI) | Accuracy % (95 % CI) | Youden index |
|---|---|---|---|---|---|---|---|
|
Basal inferoseptal segment | |||||||
| PW-DMI |
T to S'stress |
70.5 |
0.66* (0.54;0.78) |
56.7 (37.4;74.5) |
76.7 (68.1;83.9) |
72.7 (64.8;79.6) |
0.33 |
| |
S'stress- S'rest |
4.15 |
0.65* (0.53;0.76) |
56.7 (37.4;74.5) |
73.1 (64.2;80.8) |
69.8 (61.7;77.0) |
0.30 |
| |
A'stress |
12.3 |
0.64* (0.53;0.75) |
46.7 (28.3;65.7) |
81.4 (73.0;88.1) |
74.1 (66.1;81.1) |
0.28 |
| CC-DMI |
E'/A'rest |
0.64 |
0.66* (0.55;0.76) |
64.3 (44.1;81.4) |
68.2 (58.6;76.7) |
67.4 (58.9;75.1) |
0.33 |
| STI |
E'stress |
4.5 |
0.70* (0.58;0.83) |
66.7 (44.7;84.4) |
71.6 (61.0;80.7) |
70.5 (61.2;78.8) |
0.38 |
| |
E'/A'stress |
0.34 |
0.66* (0.52;0.80) |
47.6 (25.7;70.2) |
88.1 (79.2;94.1) |
80.0 (71.1;87.2) |
0.36 |
|
Mid inferoseptal segment | |||||||
| CC-DMI |
PSIstress/SSstress |
0.13 |
0.65* (0.54;0.77) |
58.1 (39.1;75.5) |
69.1 (59.6;77.6) |
66.7 (58.2;74.4) |
0.27 |
| |
SSRstress - SSRrest |
−0.21 |
0.64* (0.53;0.74) |
74.2 (55.4;88.1) |
55.9 (46.1;65.3) |
59.9 (51.3;68.0) |
0.30 |
|
Apical inferoseptal segment | |||||||
| STI |
PSIrest/SSrest |
−0.15 |
0.65*(0.54;0.76) |
70.0 (50.6;85.3) |
57.9 (48.3;67.1) |
60.4 (51.9;68.5) |
0.28 |
| |
PSIrest |
3.85 |
0.65*(0.54;0.76) |
70.0 (50.6;85.3) |
56.1 (46.5;65.4) |
59.0 (50.5;67.1) |
0.26 |
| |
RSSRrest |
1.95 |
0.63*(0.53;0.74) |
90.0 (73.5;97.9) |
34.2 (25.6;43.7) |
45.8 (37.5;54.3) |
0.24 |
|
Basal inferior segment | |||||||
| PW-DMI |
S'stress |
10.8 |
0.65* (0.53;0.76) |
48.3 (29.4;67.5) |
77.3 (68.7;84.5) |
71.6 (63.6;78.7) |
0.26 |
| |
S'stress- S'rest |
4.8 |
0.64* (0.53;0.75) |
75.9 (56.5;89.7) |
52.1 (42.8;61.3) |
56.8 (48.4;64.9) |
0.28 |
| |
T to S'stress - T to S'rest |
−45.5 |
0.64* (0.53;0.75) |
62.1 (42.3;79.3) |
65.5 (56.3;74.0) |
64.9 (56.6;72.5) |
0.28 |
| |
(T to S'stress - T to S'rest)/T to S'rest |
−0.44 |
0.66* (0.55;0.76) |
69.0 (49.2;84.7) |
58.0 (48.6;67.0) |
60.1 (51.8;68.1) |
0.27 |
| |
E'rest |
9.35 |
0.64* (0.54;0.74) |
93.3 (77.9;99.2) |
34.2 (25.8;43.4) |
46.0 (37.8;54.3) |
0.28 |
| |
E'stress |
7.53 |
0.72* (0.62;0.82) |
72.4 (52.8;87.3) |
66.1 (56.7;74.7) |
67.4 (59.1;74.9) |
0.39 |
| CC-DMI |
PSIstress/PSSstress |
0.06 |
0.65* (0.52;0.78) |
66.7 (44.7;84.4) |
61.9 (51.4;71.5) |
62.8 (53.6;71.4) |
0.29 |
| STI |
SSrest |
−13.0 |
0.65* (0.54;0.77) |
41.4 (23.5;61.1) |
88.7 (81.4;93.8) |
79.2 (71.6;85.5) |
0.30 |
|
Mid inferior segment | |||||||
| PW-DMI |
T to S'stress - T to S'rest |
−41.9 |
0.64* (0.53;0.75) |
66.7 (47.2;82.7) |
64.1 (54.7;72.8) |
64.6 (56.3;72.3) |
0.31 |
| CC-DMI |
SSstress |
−14.5 |
0.66* (0.56;0.76) |
75.0 (55.1;89.3) |
55.8 (46.1;65.1) |
59.6 (51.0;67.7) |
0.31 |
| STI |
PSSRrest |
−0.65 |
0.64* (0.52;0.76) |
41.4 (23.5;61.1) |
87.0 (79.4;92.5) |
77.8 (70.1;84.3) |
0.28 |
| |
(PSIstress - PSIrest)/PSIrest |
−0.08 |
0.67* (0.56;0.78) |
48.3 (29.4;67.5) |
81.3 (72.8;88.0) |
74.5 (66.4;81.4) |
0.30 |
|
Basal anterior segment | |||||||
| PW-DMI |
S'stress |
8.2 |
0.63* (0.52;0.74) |
75.8 (57.7;88.9) |
44.2 (34.9;53.9) |
51.4 (43.0;59.7) |
0.20 |
| CC-DMI |
S'stress |
6.2 |
0.69* (0.59;0.79) |
51.7 (32.5;70.6) |
81.3 (72.8;88.0) |
75.2 (67.2;82.1) |
0.33 |
| |
(PS'stress - PS'rest)/PS'rest |
3.1 |
0.69* (0.54;0.84) |
53.3 (26.6;78.7) |
83.1 (71.0;91.6) |
77.0 (65.8;86.0) |
0.36 |
| |
SSRstress |
−2.4 |
0.65* (0.54;0.75) |
80.0 (61.4;92.3) |
52.7 (43.0;62.2) |
58.5 (49.9;66.7) |
0.33 |
| STI |
PSIstress - PSIrest |
−5.5 |
0.64* (0.53;0.75) |
40.0 (22.7;59.4) |
87.3 (79.6;92.9) |
77.1 (69.3;83.8) |
0.27 |
| |
PSSRrest |
−1.1 |
0.68* (0.58;0.78) |
80.0 (61.4;92.3) |
47.4 (37.9;56.9) |
54.2 (45.7;62.5) |
0.27 |
| |
PSSRstress - PSSRrest |
−0.39 |
0.67* (0.56;0.78) |
80.0 (61.4;92.3) |
56.8 (47.0;66.1) |
61.7 (53.1;69.8) |
0.37 |
|
Basal inferolateral segment | |||||||
| PW-DMI |
S'stress |
12.1 |
0.65* (0.54;0.76) |
70.4 (49.8;86.2) |
57.3 (47.8;66.4) |
59.7 (51.2;67.8) |
0.28 |
| |
E'stress |
8.1 |
0.66* (0.53;0.78) |
64.0 (42.5;82.0) |
68.7 (59.4;77.0) |
67.9 (59.4;75.5) |
0.33 |
| |
E'/A'stress |
0.51 |
0.69* (0.57;0.80) |
56.0 (34.9;75.6) |
76.3 (67.4;83.8) |
72.7 (64.5;79.9) |
0.32 |
|
Mid inferolateral segment | |||||||
| CC-DMI |
E'/A'rest |
0.5 |
0.65* (0.54;0.76) |
61.5 (40.6;79.8) |
70.9 (61.5;79.2) |
69.1 (60.6;76.8) |
0.32 |
| |
SSstress |
−16.0 |
0.72* (0.62;0.82) |
80.8 (60.6;93.4) |
59.8 (50.1;69.0) |
63.8 (55.2;71.8) |
0.41 |
| |
SSRstress |
−1.4 |
0.68* (0.56;0.80) |
64.0 (42.5;82.0) |
71.2 (61.8;79.4) |
69.9 (61.4;77.4) |
0.35 |
|
Mid anteroseptal segment | |||||||
| PW-DMI |
PS'stress - PS'rest |
1.8 |
0.66* (0.55;0.76) |
86.2 (68.3;96.1) |
52.3 (42.5;62.1) |
59.6 (50.8;67.9) |
0.39 |
| |
(PS'stress - PS'rest)/PS'rest |
0.86 |
0.70* (0.58;0.82) |
81.8 (59.7;94.8) |
70.2 (59.3;79.7) |
72.6 (63.1;80.9) |
0.52 |
| CC-DMI |
E'stress |
3.5 |
0.72* (0.61;0.83) |
84.6 (65.1;95.6) |
51.2 (39.9;62.4) |
59.3 (49.4;68.6) |
0.36 |
| STI | PSIstress/SSstress | 0.14 | 0.64* (0.54;0.75) | 67.9 (47.6;84.1) | 59.0 (49.0;68.5) | 60.9 (52.1;69.2) | 0.27 |
P ≤ 0.025 for AUC > 0.5, * P < 0.05 compared with AUC of visual assessment 0.88; PW-DMI = pulsed wave Doppler myocardial imaging; CC-DMI = color coded Doppler myocardial imaging; STI = speckle tracking imaging; AUC = area under the curve; CI = confidence interval; S' = peak systolic velocity; PS' = peak post-systoloc velocity; E' = early diastolic wave; A' = late diastolic wave; SS = peak systolic strain, PSS = peak post-systolic strain; PSI = post-systolic index; SSR = systolic strain rate; PSSR = post-systolic strain rate; T = time; RSSR = radial systolic strain rate; RPSSR = radial post-systolic strain rate.