TABLE 3.
Relative Risks and Excess Relative Risks Per Gray of Cancer Mortality from In Utero Radiation Exposure among 8,000 Offspring of Female Mayak Worker Cohort Members with at Least 1 Year of Follow-Up
| Solid cancer mortality |
Leukemia mortality |
||||
|---|---|---|---|---|---|
| Person years | Cases | RR (95% CI)a | Cases | RR (95% CI)a | |
| In utero exposure status | |||||
| No | 167,119 | 47 | 1.00 (REF) | 6 | 1.00 (REF) |
| Yes | 98,419.1 | 28 | 0.94 (0.58–1.49) | 6 | 1.65 (0.52–5.27) |
| P valueb | >0.5 | 0.39 | |||
| In utero dose category | |||||
| None | 167,119 | 47 | 1.00 (REF) | 6 | 1.00 (REF) |
| >0–10 mGy | 40,065.9 | 8 | 0.94 (0.41–1.88) | 0 | NA |
| 10 mGy–<20 mGy | 13,475.1 | 7 | 1.79 (0.74–3.72) | 1 | 2.05 (0.11–11.98) |
| 20 mGy–<50 mGy | 18,223.3 | 3 | 0.45 (0.11–1.23) | 4 | 5.91 (1.51–20.79) |
| 50 mGy–<100 mGy | 10,185.1 | 4 | 1.06 (0.32–2.60) | 1 | 2.58 (0.14–15.15) |
| ≥ 00 mGy | 16,469.6 | 6 | 0.86 (0.33–1.86) | 0 | NA |
| P valueb | 0.46 | 0.03 | |||
| ERR/Gy | −0.1 (<−0.1–4.1) | −0.8 (<−0.8–46.9) | |||
| P valueb | >0.5 | >0.5 | |||
a
Relative risk (RR), excess relative risk per gray (ERR/Gy), and 95% Confidence Intervals (CIs) estimated from Poisson regression, adjusted for age and gender.
b
P values based on likelihood ratio test.