Table 2.

Age-adjusted and multivariate-adjusted hazard ratios (HR) and 95% confidence intervals (95% CI) for risk of endometrial cancer by quintiles of intake of fruits and vegetables, NIH-AARP Diet and Health Study, 1995–2003.

Intake, servings/1,000 kcal/day	No. cases	Age- adjusted HR	95% CI	MV- adjusted HR*	95% CI
Total fruit and vegetables
<1.61	198	1.00	reference	1.00	reference
1.61–<2.14	218	1.08	0.89–1.31	1.08	0.89–1.31
2.14–<2.68	271	1.33	1.10–1.59	1.32	1.09–1.60
2.68–<3.42	240	1.17	0.97–1.41	1.24	1.02–1.52
≥3.42	215	1.04	0.86–1.26	1.12	0.90–1.39
P for trend		0.81		0.28
Total fruit
<0.61	186	1.00	reference	1.00	reference
0.61–<0.97	243	1.27	1.05–1.54	1.28	1.05–1.56
0.97–<1.36	230	1.19	0.98–1.44	1.21	0.99–1.48
1.36–<1.91	252	1.29	1.07–1.56	1.36	1.11–1.67
≥1.91	231	1.18	0.97–1.43	1.30	1.04–1.61
P for trend		0.26		0.05
Total vegetables
<0.74	207	1.00	reference	1.00	reference
0.74–<1.00	246	1.18	0.98–1.42	1.17	0.97–1.41
1.00–<1.27	226	1.08	0.89–1.30	1.06	0.87–1.28
1.27–<1.67	241	1.15	0.95–1.38	1.16	0.96–1.40
≥1.67	222	1.06	0.88–1.28	1.09	0.90–1.33
P for trend		0.85		0.55

^*Adjusted for age at baseline (continuous), race/ethnicity (white, other), education (high school graduate or less, some college or more), age at menarche (<13, 13–14, ≥15), parity (none, 1, 2, ≥3, oral contraceptives (ever, never), hormone therapy (ever, never), age at menopause (premenopausal, <45, 45–49, ≥55, postmenopausal, unknown age), body mass index – kg/m² (<25, 25–29, ≥30, missing), smoking (never, former, current), frequency of vigorous physical activity (never/rarely, ≥1 time/month but <3 times/week, ≥3 times/week, missing), total fat intake (continuous), and caloric intake (continuous).