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. Author manuscript; available in PMC: 2013 Jun 1.

Published in final edited form as: J Cell Biochem. 2012 Jun;113(6):1896–1903. doi: 10.1002/jcb.24058

Immunohistochemical staining for PTTG1 protein levels demonstrates little PTTG1-protein expression in autopsy normal hearts (A) but marked increases of PTTG1 expression in tissue of patients with either aortic stenosis (B), dilated cardiomyopathy (C), systemic hypertension (D), autopsy-derived HCM (E), or myectomy-derived HCM (F). (G) This observation is quantitatively shown in bar diagram with significantly higher expression of PTTG1 detected in all hypertrophic models, except hypertrophy in the setting of systemic hypertension. Bars in white demonstrate intensity of two TIEG1-myectomy patients vs. the remaining myectomy samples.

Immunohistochemical staining for PTTG1 protein levels demonstrates little PTTG1-protein expression in autopsy normal hearts (A) but marked increases of PTTG1 expression in tissue of patients with either aortic stenosis (B), dilated cardiomyopathy (C), systemic hypertension (D), autopsy-derived HCM (E), or myectomy-derived HCM (F). (G) This observation is quantitatively shown in bar diagram with significantly higher expression of PTTG1 detected in all hypertrophic models, except hypertrophy in the setting of systemic hypertension. Bars in white demonstrate intensity of two TIEG1-myectomy patients vs. the remaining myectomy samples.