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. Author manuscript; available in PMC: 2012 Nov 12.
Published in final edited form as: J Mol Biol. 2006 Feb 10;358(1):193–212. doi: 10.1016/j.jmb.2006.01.094

Figure 9.

Figure 9

Three-dimensional models of mitochondrial and archaeal large ribosomal subunit rRNAs. Models are shown from the subunit-interface side (left) and from the solvent side (right). a. Mitochondrial rRNA, showing a dramatic reduction compared to archaea. b. H. marismortui rRNA from X-ray crystallography.30 The L1-arm (L1) was modeled using structural data from other crystallographic structures.21,38 The A-site finger (blue RNA helix adjacent to *) was modeled using sequence data and cryo-EM density from E. coli.67 Six domains in both models (a and b) are identified by different colors: I (purple), II (dark blue), III (orange), IV (green), V (red) and VI (light blue). The 5S rRNA in the archaeon (yellow) is absent in the mitoribosome. L1 proteins for both models are shown with space-filling representations (grey).