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. Author manuscript; available in PMC: 2013 Sep 21.
Published in final edited form as: Phys Med Biol. 2012 Sep 5;57(18):5809–5821. doi: 10.1088/0031-9155/57/18/5809

Table 2.

Rat data kinetic parameter estimation

Parameters Proposed closed-form methods Iterative nonlinear fitting
Function 1 (p = 0.6) Function 2 (p = 0.3) Function 3 (p = 0.7) Good Init. Cond. [0.1, 0.2, 0.3, 0.3] Bad Init. Cond. [1, 2, 3, 4]
K1 (min−1) 0.346 0.285 0.323 0.377 2.713
k2 (min−1) 0.516 0.56 0.474 0.619 7.937
k3 (min−1) 0.046 0.062 0.045 0.050 0.107
β 0.373 0.432 0.379 0.371 0.271
error 0.026 0.031 0.026 0.025 0.028